Glucose addiction can foment tumours
- Breast cancer is the top cause of cancer-related deaths in Indian women and is the most prevalent type of cancer in women.
- Worldwide statistics show that about two million new cases were detected in 2018.
- Researchers studying cancer metabolism have often noted that tumour cells are addicted to glucose.
- Once glucose enters the cell, it quickly gets fed to pathways and is utilised to multiply and grow.
- This reprogramming of glucose metabolism by cancer cells often alters the response to drugs used in cancer treatment.
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- An international team has discovered the conflicting roles of two genes in regulating glucose utilisation by breast cancer cells.
- They revealed that the CBX2 gene promotes glucose uptake and consumption by breast cancer cells whereas CBX7, a sister gene, does the opposite.


